TOXICITY TEST OF THE CROWN OF THE GOD'S PLANT FRUIT (PHALERIA MACROCARPA (Shceff.) Boerl.) AGAINST Culex sp MOSQUITO LARVA

Abstrak Mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) atau suku gaharu-gaharuan adalah salah satu anggota tumbuhan berbunga. Berdasarkan literature penelitian, tanaman mahkota mengandung senyawa alkaloid, saponin, flavonoid, lignin (polifenol, flenoida, minyak atsiri dan tannin). Kebaruan dalam penelitian ini melakukan uji toksisitas buah pada Larva Nyamuk Culex Sp. Studi bertujuan menginvestigasi efek toksik ektrak dengan konsentrasi 5%, 10%, 15%, 25% terhadap larva nyamuk culex sp menggunakan waktu pengamatan selama o detik, 30 1 menit, 5 15 60 120 menit. Desain Thepost test only controlled group design. Uji memasukan ke cawan petri yang telah disiapkan. Hasil ; ditemukan perbedaan signifikan proporsi mati setelah menit (p value = 0,001), 0,002), 0,014) pemberian ekstrak dewa, hasil menunjukan efektif terdapat Kesimpulan Kandungan lama paparan merupakan variabel penting memengaruhi persentase kematian jentik sp. Jika Dewa dinaikkan maka semakin cepat akan mati, begitu pula pengamatan, jika dinaikan lama, tinggi mati. Kata kunci: (Scheef.) Boerl.); Abstract is a member of the Thymelaeaceae family or agarwood tribe, which flowering plant tribe. Based on previous research literature, it known that contains alkaloid compounds, saponins, flavonoids, compounds (polyphenols, flenoids, essential oils and tannins. The impact mosquitoes public health filariasis also as elephantiasis disease transmitted by This study aims to investigate toxic effect extracts crown fruit at concentrations larvae used an observation time (o seconds, minute, minutes, minutes). utilizes post-test Toxicity was conducted placing mosquito in dish containing extract Dewa's with concentration had been prepared. It found There significant difference proportion died after minutes 0.001), 0.002), 0.001). 0.014) administration extract, results this showed effective within minutes. findings content duration exposure were two important variables influenced percentage mortality If increased, faster will die, well time, if increased longer, higher dead be.